Burleson has one reception for 16 yards versus the Bears on Monday and suffered a knee injury in the third quarter. Burleson has 26 receptions for 224 yards and two touchdowns through five games this season.
The Lions offense has struggled versus the Bears defense as they have failed to score while quarterback Matthew Stafford is 23-of-40 passing for just 194 yards and one interception.
Spievey suffered a concussion during the game and will not return. The Lions safety started for the first time this season against Philadelphia on October 14, recording seven tackles.
The Lions defense has played well against the Bears, holding them to one touchdown and 13 total points while limiting Jay Cutler to 16-of-31 passing for 150 yards and one touchdown.