First pitch on Saturday will be at 8:07 p.m. ET on Fox.
Sanchez is 1-1 this postseason with a 1.35 ERA and 10 strikeouts in 13.1 innings and will go against Giants starter Ryan Vogelsong. Vogelsong is 2-0 in three starts with a 1.42 ERA and 18 strikeouts in the 2012 postseason.
The Tigers will look to spark their offense in Game 3, as they only managed three runs and 10 hits in the first two games of the World Series in San Francisco to dig themselves a two-game deficit in the series.
The Tigers have lost five straight World Series games dating back to their 2006 loss to the St. Louis Cardinals in five games, but they have also won five straight playoff games at home this postseason.