Kris Medlen (5-1) gave up a run the opening frame, but held Detroit off the scoreboard for the remainder of his outing. The right-hander allowed six hits through 6 2/3 innings.
Billy Wagner struck out the side in the ninth to earn his 400th career save.
Detroit starter Andrew Oliver (0-1) absorbed the loss in his major-league debut, yielding two runs on five hits over six innings.
Oliver had his contract purchased from Double-A Erie earlier Friday.