With the Lions trying to rebound from their first loss in 10 months the early action in Vegas has them as 3.5 point favorite over the Atlanta Falcons. They are one of several home favorites this week according to the current following odds coming out of Las Vegas for week 7 in the NFL:
| Date & Time | Favorite | Spread | Underdog | Total | Money Odds |
| 10/23 1:00 ET |
Chicago Bears |
-1 |
Tampa Bay Buccaneers (At London) |
44 | -$120 +$100 |
| 10/23 1:00 ET | At Carolina Panthers |
-2.5 |
Washington Redskins |
43 | -$140 +$120 |
| 10/23 1:00 ET |
San Diego Chargers |
 -2 | At NY Jets | 43.5 | -$130 +$110 |
| 10/23 1:00 ET | At Cleveland Browns |
-3 |
Seattle Seahawks |
41 | -$160 +$140 |
| 10/23 1:00 ET | At Tennessee Titans |
-3 |
Houston Texans |
44.5 | -$180 +$160 |
| 10/23 1:00 ET | At Miami Dolphins |
-1.5 |
Denver Broncos |
43 | -$125 +$105 |
| 10/23 1:00 ET | At Detroit Lions |
-3.5 | Atlanta Falcons |
47.5 | -$185 +$165 |
| 10/23 4:05 ET | At Oakland Raiders |
-4.5 |
Kansas City Chiefs |
42 | -$220 +$190 |
| 10/23 4:05 ET |
Pittsburgh Steelers |
-3.5 | At Arizona Cardinals |
42.5 | -$195 +$170 |
| 10/23 4:15 ET | At Dallas Cowboys |
-12.5 |
St. Louis Rams |
44 | -$700 +$500 |
| 10/23 4:15 ET |
Green Bay Packers |
-9 | At Minnesota Vikings |
46.5 | -$450 +$350 |
| 10/23 8:30 ET | At New Orleans Saints |
-14 |
Indianapolis Colts |
48.5 | -$1050 +$750 |
Monday Night Football Odds
| 10/24 8:35 ET |
Baltimore Ravens |
-7.5 | At Jacksonville Jaguars |
39 | -$375 +$315 |