Detroit led 28-7 after the first quarter, but Buffalo chipped away at the lead after both teams' backups started entering the game. The Lions led 28-24 at the end of the third quarter and a 39-yard field goal by Jason Hanson less than a minute into the fourth quarter extended the lead to 31-24.
The Bills took their first lead since they led 7-0 in the first quarter when Marcus Easley returned Hanson's ensuing kickoff 100 yards for a touchdown. Buffalo went for two and converted on a pass from Tyler Thigpen to Easley for a 32-31 lead.
Detroit re-took the lead on their next drive when Kellen Moore drove the Lions 80 yards and capped off the drive with a 1-yard touchdown run.
Moore finished 17-for-30 passing for 211 yards and a rushing touchdown. Mikel Leshoure had 15 carres for 43 yards and a touchdown. The Lions didn't turn the ball over and forced four Buffalo turnovers. The Bills finished this preseason winless.
Stay with this StoryStream for more coverage of Detroit's final preseason game, and be sure to check out Pride of Detroit for more Lions news. Also visit SB Nation's NFL hub for even more coverage from around the league.