Verlander pitched eight innings, gave up eight hits and struck out 14. That ties his career high in strikeouts. He now has 1381 strikeouts in his career, passing George Mullin for sixth in Tigers history, via Brian Britten, Detroit's Director of Media Relations.
Detroit took a 2-0 lead early on the strength of solo home runs from Prince Fielder and Miguel Cabrera, but New York tied it up in the top of the fifth on RBI-singles from Derek Jeter and Robinson Cano.
RBI-singles from Omar Infante and Alex Avila plus a sac fly from Andy Dirks made it 5-2 at the end of the fifth.
Avila and Jhonny Peralta both had RBI-singles in the sixth to make it 7-2 and that's how it would stay.
Yankees starter Ivan Nova (10-6) gave up 11 hits, seven runs and struck out five in 5 1/3 innings.
Detroit sold out the game with 41,381 fans coming to Comerica Park. The series will continue Tuesday at 7:05 p.m. ET.