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Week 6 NFL lines and odds, Lions vs. Eagles: Detroit is an underdog in Week 6

The Detroit Lions are desperate for a win in Week 6, but oddsmakers have listed their opponent, the Philadelphia Eagles, as a four-point favorite heading into the weekend.

Leon Halip - Getty Images

The Detroit Lions (1-3) are coming off a bye and need to notch a win in Week 6 to avoid losing more ground on the rest of the NFC North, but odds makers have the Philadelphia Eagles (3-2) listed as 4-point favorites heading into the game at Lincoln Financial Field, according to OddsShark.com.

The line opened with Philly as a 5-point favorite, but the Lions are a stunning 0-4 against the spread this season and certainly haven't inspired any big betting action on their end. Michael Vick and the Eagles are 2-0 at home in 2012, and as noted by the experts as Odds Shark, Philadelphia is also 5-1 ATS against the Lions in six total meetings against the Lions since 1995.

The over/under for the game is at 47.5 points on most sites after opening at 48 points.

The Lions have struggled on defense so far this season, allowing 114 points over four games, but the Eagles have been burned by turnovers and have yet to break out on offense despite their star power. Detroit is one of only four NFC teams that has failed to record multiple wins in 2012. The other three are the Carolina Panthers (1-4), New Orleans Saints (1-4) and Tampa Bay Buccaneers (1-3).