Offensive tackle Jeff Backus (hamstring), safety Louis Delmas (knee), cornerback Jacob Lacey (foot and knee), defensive end Kyle Vanden Bosch (neck) and defensive tackle Corey Williams (knee) are all listed as questionable as of Friday.
A slew of players, including running back Mikel Leshoure, wide receiver Calvin Johnson and defensive end Cliff Avril are probable for Sunday's game.
Indianapolis, on the other hand, doesn't have quite as long of an injury list. Safety Tom Zbikowski (knee) is the only player ruled out for this week, while defensive tackle Martin Tevaseu (head and shoulder) is the lone Colt listed as questionable.
After not practicing Wednesday, Backus was a limited participant in Thursday and Friday's team practices. Delmas, after being limited on Thursday, did not practice Friday. Vanden Bosch appears to have recovered well, however -- after not practicing Thursday the defensive end was a full participant in Friday's team practice.